PCO-edge

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The pco.edge family of sCMOS cameras features an excellent combination of high resolution, high quantum efficiency, high frame rates and high dynamic range. All pco.edge cameras are available with various interface options and standard or deep cooling.

pco.edge provides an excellent homogeneous pixel response to light (PRNU, photo response nonuniformity) and homogeneous dark signal pixel behavior (DSNU, dark signal non-uniformity). This is achieved by taking advantage of sophisticated (FPGA based) electronic circuit technology and firmware algorithms. These outstanding qualities are clearly visible when one compares images under the same low light conditions.

Dynamic Range

The contrast between the brightest and the weakest measurable light signal in the same image defines the „intra-scene“ dynamic range of a sensor. Whereas the full well capacity sets the upper limit for the brightest signal, it is effectively the readout noise which sets the lower detection limit. With the sCMOS values of 30 000 electrons full well and around 1 electron rms readout noise, signal-to-noise can range from 88.6 - 91.1 dB, depending on camera choice.

The same extract of a larger image of neurons with a fluorescent marker for Calcium with different scaling to the 8 bit world: For all evaluations, it has been the same image! It is important that high dynamic images are properly displayed.

APPLICATION AREAS :

WIDEFIELD MICROSCOPY, FLUORESCENCE MICROSCOPY

DIGITAL PATHOLOGY

PALM, STORM, GSDIM, DSTORM, SUPER RESOLUTION MICROSCOPY

LIGHT SHEET MICROSCOPY, SELECTIVE PLANE IMAGING MICROSCOPY (SPIM)

CALCIUM IMAGING

FRET, FRAP

3D STRUCTURED ILLUMINATION MICROSCOPY

HIGH SPEED BRIGHT FIELD RATIO IMAGING

HIGH THROUGHPUT SCREENING, HIGH CONTENT SCREENING, BIOCHIP READING

PIV

TIRF, TIRF MICROSCOPY / WAVEGUIDES

SPINNING DISK CONFOCAL MICROSCOPY

LIVE CELL MICROSCOPY

3D METROLOGY

TV / BROADCASTING

OPHTALMOLOGY

ELECTRO-PHYSIOLOGY

LUCKY ASTRONOMY

PHOTOVOLTAIC INSPECTION